Since the 1980s, the learning sciences have been an emerging field of research that focuses on learning of individuals and groups in authentic social, material, and digital contexts from a multi-level perspective. The learning sciences have substantially advanced theoretical conceptions of learning and its support as well as methodological approaches, for example by introducing design-based research. The article provides an overview of the history, important theories and concepts of learning and guidance, as well as methods of the learning sciences. The concluding part sketches potentially important areas for future research in the learning sciences.